Peptide Research Hub
Educational reference
Educational reference only. Nothing on this site is medical advice. Many compounds described here are not FDA-approved, lack adequate human evidence, and may be illegal in your jurisdiction. Always consult a licensed clinician.

Research directory

Peptide compounds, organized by evidence and regulatory status

A curated reference of peptide research compounds drawn from public biomedical databases. Each entry lists mechanism summaries, regulatory status, evidence quality, safety flags, and links to peer-reviewed literature — never dosing, protocols, or sourcing.

Nootropic & Neuropeptides

P21

Nootropic & Neuropeptides reference entry

Synthetic peptide analog of ciliary neurotrophic factor (CNTF). Animal models only.

Preclinical only Not FDA-approved
Open evidence profile
Nootropic & Neuropeptides

PE-22-28

Nootropic & Neuropeptides reference entry

Spadin analog and TREK-1 modulator studied in rodent depression models.

Preclinical only Not FDA-approved
Open evidence profile
Sexual Function & Reproductive

PT-141

Bremelanotide

Melanocortin (MC4R) agonist acting centrally. FDA-approved as Vyleesi for hypoactive sexual desire disorder (HSDD) in premenopausal women.

Strong clinical FDA-approved
Open evidence profile
Skin, Hair & Aesthetic

Palmitoyl Tetrapeptide-7

Skin, Hair & Aesthetic reference entry

Cosmetic peptide studied for IL-6 modulation in keratinocyte models; used in topical anti-aging blends.

Limited human data Cosmetic / not drug-approved
Open evidence profile
Skin, Hair & Aesthetic

Palmitoyl Tripeptide-1

Pal-GHK

Lipopeptide cosmetic ingredient studied for collagen-signaling activity in topical anti-aging products.

Limited human data Cosmetic / not drug-approved
Open evidence profile
Metabolic & GLP-1/GIP Agonists

Retatrutide

Metabolic & GLP-1/GIP Agonists reference entry

Investigational triple agonist (GLP-1 / GIP / glucagon receptors) currently in Phase 3 development.

Moderate clinical Investigational
Open evidence profile
Skin, Hair & Aesthetic

SNAP-8

Skin, Hair & Aesthetic reference entry

Extended octapeptide analog of Argireline marketed in topical cosmetic preparations.

Limited human data Cosmetic / not drug-approved
Open evidence profile
Longevity & Anti-Aging

SS-31

Elamipretide

Mitochondrially targeted cardiolipin-binding peptide studied in Phase 2 trials for heart failure, kidney injury, and primary mitochondrial myopathy.

Moderate clinical Investigational
Open evidence profile
Nootropic & Neuropeptides

Selank

Nootropic & Neuropeptides reference entry

Synthetic tuftsin analog approved in Russia for generalized anxiety. Limited Western-standard clinical evidence.

Limited human data Foreign-approved only
Open evidence profile
Metabolic & GLP-1/GIP Agonists

Semaglutide

Metabolic & GLP-1/GIP Agonists reference entry

Long-acting GLP-1 receptor agonist studied extensively in type 2 diabetes and chronic weight management.

Strong clinical FDA-approved
Open evidence profile
Nootropic & Neuropeptides

Semax

Met-Glu-His-Phe-Pro-Gly-Pro

Synthetic heptapeptide analog of an ACTH fragment, approved in Russia for stroke and cognitive indications. Small human neuroimaging studies exist; no...

Limited human data Foreign-approved only 7 AA
Open evidence profile
Growth Hormone Secretagogues

Sermorelin

GHRH(1-29)

Synthetic analog of the first 29 amino acids of GHRH. Previously FDA-approved as Geref for pediatric growth hormone deficiency; commercial product...

Strong clinical Previously approved 29 AA
Open evidence profile
Healing & Tissue Repair

TB-500

Thymosin Beta-4 Synthetic Fragment

Parent protein Thymosin Beta-4 is studied for actin sequestration, cell migration, and wound healing. The marketed "TB-500" fragment lacks the parent...

Limited human data Not FDA-approved 44 AA
Open evidence profile
Growth Hormone Secretagogues

Tesamorelin

Growth Hormone Secretagogues reference entry

GHRH analog with a stabilized N-terminus. FDA-approved as Egrifta specifically for the reduction of excess abdominal fat in HIV-infected patients with...

Strong clinical FDA-approved
Open evidence profile
Longevity & Anti-Aging

Thymalin

Thymic peptide bioregulator extracted from calf thymus.

Thymic peptide complex with limited Eastern European clinical reports in elderly and immunocompromised populations.

Limited human data Not FDA-approved
Open evidence profile
Healing & Tissue Repair

Thymosin Alpha-1

Thymalfasin

Modulates T-cell function and innate immunity. Studied as an adjunct in chronic hepatitis B/C and sepsis.

Strong clinical Foreign-approved only 28 AA
Open evidence profile
Metabolic & GLP-1/GIP Agonists

Tirzepatide

Metabolic & GLP-1/GIP Agonists reference entry

Dual GLP-1/GIP receptor agonist FDA-approved for type 2 diabetes and chronic weight management.

Strong clinical FDA-approved
Open evidence profile