Peptide Research Hub
Educational reference
Educational reference only. Nothing on this site is medical advice. Many compounds described here are not FDA-approved, lack adequate human evidence, and may be illegal in your jurisdiction. Always consult a licensed clinician.

Research directory

Peptide compounds, organized by evidence and regulatory status

A curated reference of peptide research compounds drawn from public biomedical databases. Each entry lists mechanism summaries, regulatory status, evidence quality, safety flags, and links to peer-reviewed literature — never dosing, protocols, or sourcing.

Reset
Longevity & Anti-Aging

Epithalon

Alanyl-Glutamyl-Aspartyl-Glycine (AEDG tetrapeptide)

Synthetic tetrapeptide studied by the Khavinson research group for putative telomerase activation and pineal-modulating effects. Independent replication is limited.

Preclinical only Not FDA-approved 4 AA
Open evidence profile
Longevity & Anti-Aging

FOXO4-DRI

Longevity & Anti-Aging reference entry

Senolytic peptide that disrupts FOXO4–p53 interaction; studied in aged mice for clearance of senescent cells. No human clinical data.

Preclinical only Not FDA-approved
Open evidence profile
Longevity & Anti-Aging

Humanin

Apoptosis regulator BAX

Mitochondrial-derived peptide studied in neuroprotection and metabolic regulation; early correlational human data.

Preclinical only Not FDA-approved 24 AA
Open evidence profile
Longevity & Anti-Aging

MOTS-c

Cyclic AMP-dependent transcription factor ATF-1

Studied for metabolic regulation, insulin sensitivity, and exercise adaptation in animal models and early human pharmacokinetic studies.

Limited human data Not FDA-approved 16 AA
Open evidence profile
Longevity & Anti-Aging

SS-31

Elamipretide

Mitochondrially targeted cardiolipin-binding peptide studied in Phase 2 trials for heart failure, kidney injury, and primary mitochondrial myopathy.

Moderate clinical Investigational
Open evidence profile
Longevity & Anti-Aging

Thymalin

Thymic peptide bioregulator extracted from calf thymus.

Thymic peptide complex with limited Eastern European clinical reports in elderly and immunocompromised populations.

Limited human data Not FDA-approved
Open evidence profile