Healing & Tissue Repair
KPV
Lysine-Proline-Valine tripeptide
Also known as: Lys-Pro-Val
Mechanism & research context
Preclinical studies suggest NF-κB pathway inhibition and reduced inflammatory cytokine output in mucosal models.
Origin: C-terminal tripeptide of alpha-MSH; investigated as an anti-inflammatory fragment.
Safety flags
0 flagsNo curator-recorded safety flags for this entry. Absence of recorded flags is not evidence of safety. Many peptides lack adequate human data.
Research papers
16 recordsCitation links route to PubMed, Europe PMC, and PMC. Presence of a study is not endorsement. Records are refreshed from PubMed on a regular cadence; rows marked “Live search link” will resolve to a current PubMed search until a full citation has been ingested.
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· 2026
NLRP3 autophagic degradation disruption in melanocytes contributes to vitiligo development.
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· 2026 Open access
Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers.
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· 2026 Open access
Mechanistic studies of hydrogels in oral cancer treatment: Synergistic effects of drug delivery and immune modulation.
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· 2026
A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review.
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· 2026
Lysine-proline-valine peptide attenuates hepatic lipid accumulation through ROS-dependent regulation of the PPARγ pathway in HepG2 cells.
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· 2025
Lysine-Proline-Valine peptide mitigates fine dust-induced keratinocyte apoptosis and inflammation by regulating oxidative stress and modulating the MAPK/NF-κB pathway.
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· 2025 Open access
Clinical efficacy and safety of two highly purified human menopausal gonadotropins in women undergoing in vitro fertilization.
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· 2025
Early Onset Neonatal Sepsis: Is Source Identification Proving Elusive?
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· 2025 Open access
Recent advances in albumin-based nanoparticle drug delivery systems for intestinal disease treatment.
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· 2025 Open access
Exploring the Role of Tripeptides in Wound Healing and Skin Regeneration: A Comprehensive Review.
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· 2025
Host defense peptides as a new drug lead to a strategy for inflammatory bowel disease.
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· 2024 Open access
Design of Mixed-Mode Analog PID Controller with CFOAs.
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· 2024 Open access
PepT1-targeted nanodrug based on co-assembly of anti-inflammatory peptide and immunosuppressant for combined treatment of acute and chronic DSS-induced ColitiS.
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· 2024
KPV and RAPA Self-Assembled into Carrier-Free Nanodrugs for Vascular Calcification Therapy.
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· 2024
Early treatment of skeletal class III malocclusion with facemask therapy in Vietnam.
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Review · PubMed (NCBI) Live search link
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Clinical trials
1 record-
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Doses reported in studies
0 recordsNo study-protocol dose records have been curated for KPV yet. Absence of records is not evidence of safety — many peptides lack adequate human-trial data in the first place.
Records here are populated from public sources only (ClinicalTrials.gov protocol summaries and FDA-approved labels) and must cite a verifiable source URL. They are not added from forum posts, vendor pages, anecdotal write-ups, or social media.
These entries describe what was studied. They do not tell you what to take, how to reconstitute anything, how to fill a capsule, how often to administer, or where to obtain a compound. If you are considering use of KPV, those decisions belong with a licensed clinician working from the full label or trial record — not from this summary.
Why this page does not list a dose for self-use
The "Doses reported in studies" section above (when populated) describes what was administered in a cited study or label, under medical supervision, in a specific population. It is not a dosing guide for self-use. Separately, we do not publish anecdotal or community-reported dose ranges, administration methods, vial concentrations, or capsule masses for KPV. Anecdotal figures for unapproved compounds are not harm-reduction data: they lack denominators for adverse events, cannot account for individual physiology or compound purity, and normalise unsupervised use. See the safety policy for the full reasoning.
If this compound has an FDA-approved label
If a label exists, the regulator-reviewed dosing and administration information is there — read it in the context of a prescriber's evaluation.
Questions worth bringing to a clinician
- What is the evidence for this compound in someone with my history?
- What are the realistic, regulator-reviewed alternatives?
- What would you monitor, and what would make you stop?
If you have already taken a peptide and feel unwell: contact emergency services. In the United States, Poison Control is reachable 24/7 at 1-800-222-1222. Do not wait for a community thread.