Nootropic & Neuropeptides
Cerebrolysin
Mechanism & research context
Mixture of low-molecular-weight peptides from porcine brain tissue. Studied in dementia and stroke; approved in some European and Asian countries. Not FDA-approved.
Origin: Porcine brain-derived peptide extract.
Safety flags
0 flagsNo curator-recorded safety flags for this entry. Absence of recorded flags is not evidence of safety. Many peptides lack adequate human data.
Research papers
16 recordsCitation links route to PubMed, Europe PMC, and PMC. Presence of a study is not endorsement. Records are refreshed from PubMed on a regular cadence; rows marked “Live search link” will resolve to a current PubMed search until a full citation has been ingested.
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· 2026
Cerebroprotection in acute ischemic stroke: Perspectives on combining cerebrolysin with recanalization therapy.
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· 2026
[Experience of using of Cerebrolysin in comprehensive rehabilitation of a patient after ischemic stroke with motor deficit and aphasia].
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· 2026 Open access
Cerebrolysin after Endovascular Thrombectomy in Stroke: 12‑Month Functional Outcomes in a Propensity‑Matched Cohort.
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· 2026 Open access
Cerebrolysin and Risk of Hemorrhagic Transformation: A Pooled Analysis of Recent Studies.
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· 2026
[The effect of Cerebrolysin on the development of skills in patients after acute cerebrovascular accidents].
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· 2026
[The effect of neuroprotectors on the level of BDNF, tumor necrosis factor alpha and apoptosis markers, and in acute cerebrovascular accidents].
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· 2026
Editorial Expression of Concern: Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin.
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· 2026
Retraction Note: Neurotrophic effects of Cerebrolysin in the Mecp2<sup>308/Y</sup> transgenic model of Rett syndrome.
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· 2026 Open access
Efficacy and Safety of Cerebrolysin as an Adjunct to Mechanical Thrombectomy in Acute Ischemic Stroke: A Systematic Review and Meta-Analysis of Observational Studies.
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· 2026
Retraction Note to: Timed Release of Cerebrolysin Using Drug-Loaded Titanate Nanospheres Reduces Brain Pathology and Improves Behavioral Functions in Parkinson's Disease.
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· 2026
Retraction: Regional Comparison of the Neurogenic Effects of CNTF-Derived Peptides and Cerebrolysin in AβPP Transgenic Mice.
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· 2026
[Therapy prospects for post-stroke aphasia].
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· 2025 Open access
Combined citicoline and Cerebrolysin for neuroprotection in traumatic brain injury: a retrospective cohort analysis.
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· 2025 Open access
Surgical excision of cerebral glioma and multimodal treatment including Cerebrolysin: a case report.
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· 2025 Open access
Cerebrolysin, hemorrhagic transformation, and anticoagulation timing after reperfusion therapy in stroke: <i>post hoc</i> secondary analysis of the CEREHETIS trial.
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Review · PubMed (NCBI) Live search link
PubMed literature search: Cerebrolysin
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Clinical trials
21 records-
Live search Live search
Live ClinicalTrials.gov search: Cerebrolysin
Condition: See live results
Open on ClinicalTrials.gov ↗ -
NCT00868283 PHASE4 COMPLETED
A Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Safety and Efficacy of Cerebrolysin in Patients With Acute Ischemic Stroke
Condition: Ischemic Stroke
Sponsor: Ever Neuro Pharma GmbH
Open on ClinicalTrials.gov ↗ -
NCT00911807 PHASE2 COMPLETED
A Randomized, Double-Blind, Clinical Trial to Compare the Safety and Efficacy of Cerebrolysin and Aricept (Donepezil) and a Combination Therapy in Patients With Probable Alzheimer's Disease (AD)
Condition: Alzheimer Disease
Sponsor: Ever Neuro Pharma GmbH
Open on ClinicalTrials.gov ↗ -
NCT01388738 PHASE3 COMPLETED
Navigation Brain Stimulation (NBS) for Evaluation of the Neuroprotective Drug Efficiency in Patients After Ischemic Stroke.
Condition: Stroke
Sponsor: Clinical Institute of the Brain, Russia
Open on ClinicalTrials.gov ↗ -
NCT01606111 PHASE4 TERMINATED
A Randomized, Double-blind, Placebo-controlled Trial to Investigate Safety and Efficacy of Cerebrolysin in Patients With Traumatic Brain Injury
Condition: Traumatic Brain Injury
Sponsor: Ever Neuro Pharma GmbH
Open on ClinicalTrials.gov ↗ -
NCT02116348 PHASE2 UNKNOWN
Effect of Nerve Growth Factor (Cerebrolysin) Therapy on Neurodevelopment, Sleep Pattern and Quality of Life in Children With Traumatic Brain Injury and Cerebral Palsy
Condition: Cerebral Palsy Children; Children With Traumatic Brain Injury; Mental Handicap; Delayed Speech Development
Sponsor: Ain Shams University
Open on ClinicalTrials.gov ↗ -
NCT02149875 PHASE1 COMPLETED
A Comparison of Safety and Efficacy of Dl-3-n-butylphthalide and Cerebrolysin on Neurological and Behavioral Outcomes in Acute Ischemic Stroke: a Randomized, Double-blind Study.
Condition: Acute Cerebral Stroke Within 12 Hours for the First Time
Sponsor: Shanghai 6th People's Hospital
Open on ClinicalTrials.gov ↗ -
NCT02581371 PHASE4 UNKNOWN
Randomized, Double-blind, Placebo-controlled Study of the Effect of Cerebrolysin® (EVER Neuro Pharma GmbH, Austria) at the Level of Paresis of the Upper Limb When Used in Complex Therapy of Acute Ischemic Stroke
Condition: Ischemic Stroke
Sponsor: Clinical Institute of the Brain, Russia
Open on ClinicalTrials.gov ↗ -
NCT03480698 COMPLETED
C-REGS2 - a Registry Study to Observe Clinical Practices, Safety and Efficiency of Routine Use of Cerebrolysin in the Treatment of Patients with Moderate to Severe Neurological Deficits After Acute Ischaemic Stroke
Condition: Acute Ischemic Stroke
Sponsor: Ever Neuro Pharma GmbH
Open on ClinicalTrials.gov ↗ -
NCT04124367 PHASE2 TERMINATED
IMPULSE StIMulation of Brain Plasticity to Improve Upper Limb Recovery After StrokE A Prospective, Multi-center, Randomized, Double-blind Study to Assess Efficacy and Safety of Neuroplastic Intervention by Cerebrolysin and atDCS on Motor Function Recovery in Subacute and Chronic Stroke Patients
Condition: Chronic Stroke; Subacute Stroke
Sponsor: Ever Neuro Pharma GmbH
Open on ClinicalTrials.gov ↗ -
NCT04751136 PHASE2 COMPLETED
Phase (2) Clinical Trial Studying the Effect of Cerebrolysin on Physical and Mental Functions of Down Syndrome
Condition: Down Syndrome
Sponsor: Mansoura University Children Hospital
Open on ClinicalTrials.gov ↗ -
NCT05288465 NA COMPLETED
Hair Repigmentation in Patients Undergoing on Cerebrolysin Treatment for Neurological Diseases.
Condition: Hair Problems
Sponsor: Universidad Autonoma de Nuevo Leon
Open on ClinicalTrials.gov ↗ -
NCT05821075 PHASE1 RECRUITING
Comparative Study Between Prednisolone, Cerebrolysin in the Treatment of Bell's Palsy
Condition: Bell Palsy
Sponsor: October 6 University
Open on ClinicalTrials.gov ↗ -
NCT05864677 NA UNKNOWN
Efficacy of Cerebrolisin in the Prevention of Postoperative Delirium in Cardiac Surgery Patients
Condition: Neurocognitive Disorders; Surgery-Complications; Critical Illness; Brain Damage; Cardiac Disease
Sponsor: Medical University of Lublin
Open on ClinicalTrials.gov ↗ -
NCT06052787 PHASE3 COMPLETED
The Impact and Outcomes of Combined Cerebrolysin and Amantadine Sulfate Administration on Management of Patients With Traumatic Brain Injury in the ICU
Condition: Traumatic Brain Injury
Sponsor: Ain Shams University
Open on ClinicalTrials.gov ↗ -
NCT06078215 PHASE4 UNKNOWN
CERebrolysine Effect on Blood-brain Barrier / Endothelium Integrity During Reperfusion Therapy of acUte Ischemic Stroke (CERBERUS Study)
Condition: Acute Ischemic Stroke
Sponsor: Poznan University of Medical Sciences
Open on ClinicalTrials.gov ↗ -
NCT06208540 PHASE4 COMPLETED
Persistent Olfactory and Gustatory Dysfunctions Due to Different SARS-CoV-2 Variants: Clinical Characteristics and Treatment
Condition: Post-covid-19 Persistent Smell and Taste Disorders
Sponsor: Sherifa Ahmed Hamed
Open on ClinicalTrials.gov ↗ -
NCT06429943 COMPLETED
Cerebrolysin in Patients Diagnosed With SAH - an Observational Cohort Study (PILOT)
Condition: SAH (Subarachnoid Hemorrhage)
Sponsor: Pomeranian Medical University Szczecin
Open on ClinicalTrials.gov ↗ -
NCT06677502 NA ENROLLING_BY_INVITATION
The Usefulness of Cerebrolysin in Alleviating the Severity of Delirium in Critically Ill Patients
Condition: Cognitive Impairment
Sponsor: Medical University of Lublin
Open on ClinicalTrials.gov ↗ -
NCT06897176 PHASE4 RECRUITING
Effects of Cerebrolysin on Language Ability in Non-fluent Aphasia Patients After Stroke: A Randomized, Placebo-controlled, Double-blinded, Single Center Study
Condition: Stroke
Sponsor: Yonsei University
Open on ClinicalTrials.gov ↗ -
NCT06899464 PHASE4 NOT_YET_RECRUITING
Safety and Feasibility of Using Cerebrolysin in the Treatment of Primary Intracerebral Hemorrhage
Condition: Intracerebral Hemorrhage; Hemorrhagic Stroke, Intracerebral; Hemorrhagic Stroke; Stroke
Sponsor: Cardinal Stefan Wyszynski University
Open on ClinicalTrials.gov ↗
Doses reported in studies
0 recordsNo study-protocol dose records have been curated for Cerebrolysin yet. Absence of records is not evidence of safety — many peptides lack adequate human-trial data in the first place.
Records here are populated from public sources only (ClinicalTrials.gov protocol summaries and FDA-approved labels) and must cite a verifiable source URL. They are not added from forum posts, vendor pages, anecdotal write-ups, or social media.
These entries describe what was studied. They do not tell you what to take, how to reconstitute anything, how to fill a capsule, how often to administer, or where to obtain a compound. If you are considering use of Cerebrolysin, those decisions belong with a licensed clinician working from the full label or trial record — not from this summary.
Why this page does not list a dose for self-use
The "Doses reported in studies" section above (when populated) describes what was administered in a cited study or label, under medical supervision, in a specific population. It is not a dosing guide for self-use. Separately, we do not publish anecdotal or community-reported dose ranges, administration methods, vial concentrations, or capsule masses for Cerebrolysin. Anecdotal figures for unapproved compounds are not harm-reduction data: they lack denominators for adverse events, cannot account for individual physiology or compound purity, and normalise unsupervised use. See the safety policy for the full reasoning.
If this compound has an FDA-approved label
If a label exists, the regulator-reviewed dosing and administration information is there — read it in the context of a prescriber's evaluation.
Questions worth bringing to a clinician
- What is the evidence for this compound in someone with my history?
- What are the realistic, regulator-reviewed alternatives?
- What would you monitor, and what would make you stop?
If you have already taken a peptide and feel unwell: contact emergency services. In the United States, Poison Control is reachable 24/7 at 1-800-222-1222. Do not wait for a community thread.